Atsuo Takashima Selected Research

Panitumumab (Vectibix)

2/2024	Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer.
1/2023	Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial.
9/2022	Primary tumor location as a predictor of survival in patients with RAS wild-type colorectal cancer who receive molecularly targeted drugs as first-line therapy: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon and Rectum.
5/2022	Topical corticosteroid therapy for facial acneiform eruption due to EGFR inhibitors in metastatic colorectal cancer patients: a randomized controlled trial comparing starting with a very strong or a weak topical corticosteroid (FAEISS study, NCCH1512, colorectal part).
1/2022	Multicentre single-arm phase II trial evaluating the safety and effiCacy of Panitumumab and iRinOtecan in NeoRAS Wild-type mEtaStatic colorectal cancer patientS (C-PROWESS trial): study protocol.
7/2021	Efficacy and safety of topical benzoyl peroxide for prolonged acneiform eruptions induced by cetuximab and panitumumab: A multicenter, phase II trial.
1/2021	Panitumumab-Associated Drug-Induced Immune Thrombocytopenia in a Patient with Colorectal Cancer.
11/2019	Primary Tumor Resection for Stage IV Colorectal Cancer in the Era of Targeted Chemotherapy.
1/2018	A Prospective, Multicenter Phase II Study of the Efficacy and Feasibility of 15-minute Panitumumab Infusion Plus Irinotecan for Oxaliplatin- and Irinotecan-refractory, KRAS Wild-type Metastatic Colorectal Cancer (Short Infusion of Panitumumab Trial).
9/2016	A phase I study of the combination of panitumumab and bevacizumab in KRAS wild-type colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, irinotecan and bevacizumab.

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Atsuo Takashima Research Topics

Disease

55	Neoplasms (Cancer) 02/2024 - 01/2008
52	Colorectal Neoplasms (Colorectal Cancer) 03/2024 - 01/2009
44	Stomach Neoplasms (Stomach Cancer) 01/2024 - 08/2008
23	Neoplasm Metastasis (Metastasis) 01/2024 - 02/2010
11	Esophageal Squamous Cell Carcinoma 03/2024 - 12/2014
10	Adenocarcinoma 03/2024 - 01/2008
10	Disease Progression 01/2021 - 05/2011
6	Neutropenia 10/2023 - 10/2013
6	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2023 - 10/2009
6	Carcinoma (Carcinomatosis) 02/2021 - 04/2015
5	Esophageal Neoplasms (Esophageal Cancer) 03/2024 - 12/2014
4	Rectal Neoplasms (Rectal Cancer) 11/2023 - 05/2017
4	Residual Neoplasm 01/2023 - 02/2009
4	Hemorrhage 04/2021 - 08/2009
3	Hypertension (High Blood Pressure) 01/2024 - 12/2012
3	Colonic Neoplasms (Colon Cancer) 09/2022 - 01/2018
3	Acneiform Eruptions 05/2022 - 01/2019
3	Ascites 12/2020 - 01/2012
3	Anorexia 01/2020 - 08/2010
3	Neuroendocrine Carcinoma 01/2020 - 09/2014
3	Diarrhea 10/2019 - 08/2010
2	Brain Neoplasms (Brain Tumor) 08/2023 - 07/2019
2	Exanthema (Rash) 01/2023 - 09/2016
2	Head and Neck Neoplasms (Head and Neck Cancer) 07/2021 - 03/2019
2	Mesothelioma 03/2021 - 12/2019
2	Malignant Mesothelioma 03/2021 - 12/2019
2	Thrombocytopenia (Thrombopenia) 01/2021 - 01/2020
2	Wounds and Injuries (Trauma) 10/2020 - 04/2015
2	Lung Neoplasms (Lung Cancer) 10/2019 - 06/2009
2	Mucositis 10/2019 - 09/2016
2	Febrile Neutropenia 01/2017 - 08/2010
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2016 - 09/2014
2	Biliary Tract Neoplasms (Biliary Tract Cancer) 09/2013 - 12/2010
2	Nausea 08/2010 - 07/2009
1	COVID-19 02/2024

Drug/Important Bio-Agent (IBA)

20	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 01/2008
18	Fluorouracil (Carac)FDA LinkGeneric 03/2024 - 08/2008
17	Irinotecan (Camptosar)FDA LinkGeneric 01/2023 - 01/2008
16	Bevacizumab (Avastin)FDA Link 03/2024 - 05/2012
12	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2024 - 12/2012
12	Biomarkers (Surrogate Marker)IBA 02/2024 - 05/2012
11	Panitumumab (Vectibix)FDA Link 02/2024 - 07/2016
11	ErbB Receptors (EGF Receptor)IBA 09/2023 - 01/2009
10	trifluridine tipiracil drug combinationIBA 10/2023 - 01/2018
8	PlatinumIBA 01/2022 - 12/2014
8	regorafenibIBA 01/2022 - 01/2018
7	Cetuximab (Erbitux)FDA Link 03/2024 - 07/2016
7	NivolumabIBA 01/2024 - 01/2019
6	Leucovorin (Folinic Acid)FDA Link 03/2024 - 08/2008
6	Paclitaxel (Taxol)FDA LinkGeneric 04/2020 - 08/2008
5	Docetaxel (Taxotere)FDA Link 03/2024 - 12/2014
5	RamucirumabIBA 07/2023 - 07/2017
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2023 - 02/2009
4	Monoclonal AntibodiesIBA 01/2023 - 01/2018
4	130-nm albumin-bound paclitaxelIBA 01/2020 - 01/2017
3	Immune Checkpoint InhibitorsIBA 01/2023 - 10/2019
3	S-1 plus cisplatinIBA 01/2022 - 12/2013
3	C-Reactive ProteinIBA 11/2021 - 07/2010
3	Taxoids (Taxanes)IBA 03/2021 - 12/2014
3	Trastuzumab (Herceptin)FDA Link 11/2019 - 10/2014
2	Epidermal Growth Factor (EGF)IBA 02/2024 - 09/2022
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2024 - 10/2019
2	Calcibiotic Root Canal SealerIBA 10/2023 - 01/2020
2	Carcinoembryonic AntigenIBA 09/2023 - 10/2016
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 08/2023 - 05/2011
2	Therapeutic UsesIBA 01/2023 - 02/2022
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2023
2	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2022 - 07/2021
2	andecaliximabIBA 01/2022 - 01/2022
2	EnzymesIBA 01/2022 - 01/2019
2	ParaffinIBA 04/2021 - 04/2014
2	Formaldehyde (Formol)FDA Link 04/2021 - 04/2014
2	Pemetrexed (MTA)FDA Link 03/2021 - 12/2019
2	Capecitabine (Xeloda)FDA Link 01/2021 - 10/2014
2	SolventsIBA 01/2020 - 01/2017
2	Antineoplastic Agents (Antineoplastics)IBA 08/2019 - 02/2011
2	AntibodiesIBA 01/2019 - 01/2016
2	Serum AlbuminIBA 12/2018 - 07/2010
2	taxaneIBA 09/2017 - 12/2014
2	LigandsIBA 08/2016 - 05/2015
2	Indicators and Reagents (Reagents)IBA 01/2016 - 04/2014
2	Methotrexate (Mexate)FDA LinkGeneric 10/2013 - 02/2010
2	Gemcitabine FDA Link 09/2013 - 12/2010
1	olaparibIBA 03/2024
1	binimetinibIBA 03/2024
1	encorafenibIBA 03/2024
1	VaccinesIBA 02/2024
1	COVID-19 VaccinesIBA 02/2024

Therapy/Procedure

71	Drug Therapy (Chemotherapy) 03/2024 - 01/2008
33	Therapeutics 03/2024 - 08/2008
12	Chemoradiotherapy 03/2024 - 10/2009
7	Gastrectomy 01/2023 - 02/2009
6	Radiotherapy 08/2023 - 08/2009
4	Adjuvant Chemotherapy 05/2021 - 01/2017
4	Combination Drug Therapy (Combination Chemotherapy) 05/2018 - 01/2008
3	Aftercare (After-Treatment) 01/2024 - 01/2014
2	Neoadjuvant Therapy 11/2023 - 08/2018
2	Intravenous Infusions 01/2022 - 02/2011
2	Immunotherapy 01/2021 - 01/2019
2	Esophagectomy 08/2018 - 01/2017